GO:0016469 cellular_component proton-transporting two-sector ATPase complex
| PAG Title | GO:0016469 cellular_component proton-transporting two-sector ATPase complex |
| PAG ID | TAX019040 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 2,680 |
| Information Content | Rich |
| Other IDs | GO:0016469 |
| Base PAG ID | TAX019040 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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